Question

1. What is the basic difference between M3 and M3v

2. Write diagnostic criteria of M4 and M4 eos

3. How can You differentiate Pure Erythroleukemia from simple m7?

4. Why MPO and SBB is almost Negative in M4 ,M5



5. Write down Specific markers of M6 and M7 ​

Answer 1

Explanation:

The cytomorphology of APL blasts is obviously different in the two subtypes: in AML M3, the abnormal promyelocytes show a heavy granulation and bundles of Auer rods; in AML M3v blasts have a non- or hypogranular cytoplasm or contain fine dustlike cytoplasmic granules that may not be apparent by light microscopy.