1. What were the physical problems of the three men of Jewish descent?
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There are several autosomal recessive genetic disorders that are more common in ethnically Jewish populations, particularly Ashkenazi Jews, than the population as a whole. This is due to population bottlenecks that occurred relatively recently in the past as well as a practice of consanguineous marriage.[1] These two phenomena lead to a decrease in genetic diversity and a higher likelihood that two parents will carry a mutation in the same gene and pass on both mutations to a child.
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