1. Which among the following defines GPI anchored proteins?
• Integral proteins of the plasma membrane
• Peripheral proteins of the plasma membrane
• Proteins that bind to ion-gated channels in the plasma membrane
•proteins which randomly bind to lipids oc the plasma membrane
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Answers
Answer:
Glycosylphosphatidylinositol (About this soundpronunciation (help·info)), or glycophosphatidylinositol, or GPI in short, is a phosphoglyceride that can be attached to the C-terminus of a protein during posttranslational modification. Proteins containing a GPI anchor play key roles in a wide variety of biological processes.It is composed of a phosphatidylinositol group linked through a carbohydrate-containing linker (glucosamine and mannose glycosidically bound to the inositol residue) and via an ethanolamine phosphate (EtNP) bridge to the C-terminal amino acid of a mature protein. The two fatty acids within the hydrophobic phosphatidyl-inositol group anchor the protein to the cell membrane.
GPI synthesis components
Identifiers:-
Symbol : GPI
Membranome : 327
Answer:proteins which randomly bind to lipids of the plasma membrane
Explanation: As G P 1 proteins have two fatty acids they bind to lipids