12. Replication of the genome occurs in the _____ phase of the cell cycle
Answers
During the G1 phase, the cell grows and prepares for DNA replication, which occurs in the subsequent S phase.
Answer:
Replication of the genome occurs in the S phase of the cell cycle.
Explanation:
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As per the questions it is given that
Replication of the genome occurs in the _____ phase of the cell cycle.
The interphase is characterized by three major phases, G1 phase, S phase, and G2 phase.
S phase or the synthesis phase is the part of the cell cycle in which DNA is replicated, occurring between G1 phase and G2 phase.
A complete cell cycle comprises four stages namely G1, S, G2 and M phases. Out of these four stages, G1, S & G2 phases constitute the interphase period after the completion of which the cell enters the mitotic phase i.e., the division phase.
The events occurring in Interphase or non-division phase are –
G1 phase: At the end of one cell division, the post mitotic gap phase (G1) occurs. RNA and protein synthesis takes place during this phase.
S phase: S phase or synthesis phase involves DNA synthesis from purine and pyrimidine nucleotides. Replication of chromosomal DNA takes place in this phase and histones are also synthesized.
G2 phase: During the pre-mitotic gap phase (G2) all the metabolic activities related to the growth of cytoplasm and of its constituent organelles and macromolecules are performed. Protein and RNA synthesis takes place in this phase, however, DNA synthesis stops.
Hence, Replication of the genome occurs in the S phase of the cell cycle.
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