18. The disease sickle cell anaemia is controlled by a single pair of alleles-Hb' and Hb
a) Which allele produce abnormal Polypeptide chain
b) What is the abnormality in polypeptide chain
c) What is the reason for this abnormality
d) What will be the effect of this change in polypeptide chain
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Answer:
Hb'
RBC becomes sickle shaped
substitution of glutamic acid by valine
oxygen deficiency and anaemia
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