2 For Krebs cycle replenishment of which of the following is not required
(A) NAD
(B) FAD
(C) OAA
(D) Oxygen
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Answer:
d is the answer hope u get it
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Answer: Option (D) Oxygen is the correct answer.
Although oxygen is required for the final stage of aerobic cellular respiration, oxidative phosphorylation, the Krebs cycle does not require it on its own.
What is Krebs Cycle?
- An essential cell's metabolic centre is the tricarboxylic acid (TCA) cycle, sometimes referred to as the Krebs cycle or citric acid cycle.
- With the exception of the oddball succinate dehydrogenase, which is connected to the respiratory chain on the inner mitochondrial membrane, it is made up of eight enzymes, all of which are found within the mitochondrial matrix.
- For compounds that can transform into an acetyl group or dicarboxylic acid, the cycle acts as a portal for aerobic metabolism.
- The three enzymes citrate synthase, isocitrate dehydrogenase, and alpha-ketoglutarate dehydrogenase are involved in three different places where the TCA cycle is regulated.
- The cycle also contributes to the replenishment of precursors for the storage form of fuels, including cholesterol and amino acids.
- Carbohydrates, lipids, and proteins are among the organic substances having energy that are split in earlier reactions. They change into acetyl-CoA, a molecule made up of an acetyl group (CH3CO-) and an acyl transporter known as coenzyme A, prior to entering the Krebs cycle.
- However, glycolysis continues to be the predominant source of acetyl-CoA. The acetyl group is then oxidised, and the energy produced is used in conjunction with oxidative phosphorylation to produce ATP.
- The Krebs cycle processes occur in the mitochondrial matrix, a dense solution that surrounds the mitochondrial crests in eukaryotes.
- In addition to water, the matrix also includes all the enzymes, coenzymes, and phosphates required for the cycle's biochemical reactions. High NADH concentrations impede the Krebs cycle, which is controlled and regulated by the availability of the NAD+ and FAD substrates.
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