2) had/toxicities/compound/ significant/the
3) additional/malaria/types/certain/of/requires/medication
4) bark/took/it/centuries/two/the/isolated/the for/from/bark/be/Quinine
5) include/effects/common/adverse/other/itching/headache/and
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2.The compound had significant toxicities.
3. Malaria requires certain types of additional medication.
4. --- sorry it was confusing so I couldn't get it
5.Other common effects include adverse itching and headache.
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