Question

20.
Calculate the dose of Ceftriaxone in ml for meningitis for 5 years old weighing 18
kg. The dose required is 100 mg/kg/day given i.v. once daily. The drug has
concentration of 40 mg/ml.​

Answer 1

Answer:

Most drugs in children are dosed according to body weight (mg/kg) or body surface area (BSA) (mg/m2). Care must be taken to properly convert body weight from pounds to kilograms (1 kg= 2.2 lb) before calculating doses based on body weight. Doses are often expressed as mg/kg/day or mg/kg/dose, therefore orders written "mg/kg/d," which is confusing, require further clarification from the prescriber.

Chemotherapeutic drugs are commonly dosed according to body surface area, which requires an extra verification step (BSA calculation) prior to dosing. Medications are available in multiple concentrations, therefore orders written in "mL" rather than "mg" are not acceptable and require further clarification.

Dosing also varies by indication, therefore diagnostic information is helpful when calculating doses. The following examples are typically encountered when dosing medication in children.

Answer 2

Answer:

It is necessary first to estimate the total daily Dose based on the child's weight and the prescribed dosage to calculate the Dose of ceftriaxone in ml for meningitis for a five-year-old weighing 18 kg.

Explanation:

Ceftriaxone for meningitis should be administered at 100 milligrammes per kilogramme each day. This means that the total daily dosage for an 18-kilogram youngster would be:

Daily Dose = 1800 Mg (100% of 18 kg)

Secondly, knowing that the concentration of ceftriaxone solution is 40 mg/ml, determine how many millilitres contain 1800 milligrammes of the antibiotic.

For this purpose, we may utilise the following equation:

Measurable drug concentration (mg/ml) Equals total drug dosage (mg)

With the available data, we can:

Calculating the millilitre volume of the medication solution: 1800 mg x 40 mg/ml x 45 ml

A 5-year-old weighing 18 kg would need 45 ml of ceftriaxone to treat meningitis.

An experienced medical expert only gives ceftriaxone by intravenous infusion. In addition, a doctor should evaluate the Dose and length of therapy depending on the child's specific condition and medical history. To ensure the infection is fully treated, following the doctor's orders and finishing the whole course of therapy is crucial.

To learn more about ceftriaxone, click on the link below.

https://brainly.com/question/7251479

To learn more about meningitis, click on the link below.

https://brainly.in/question/8357942

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