23) In the given figure of human hand pedigree analysis is given
mother father
1
daughter daughter son/daughter
In the above pedigree which character is represented and what is the probability of disease
occurrence in fifth child?
(a) Polydactyly (autosomal dominant disorder), 50%
(b) Polydactyly (autosomal recessive disorder), 50%
(c) Polydactyly (X-linked dominant disorder). 50%
(d) Polydactyly CX-linked recessive disorder). 50%
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Answer: Autosomal Dominant, 50%
Explanation: It is autosomal dominant because though a parent is affected, there are unaffected children. The trait doesn't skip generations, so it is dominant. It is autosomal because it is not sex specific, that is, both son and daughter is affected.
The probability for the fifth child to get a disease is 100%, but that child can be either a son or a daughter. And only one of them can get affected. So the percentage becomes 50%.
The disorder is Polydactyly.
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