3. A strain of mice specifically lacking
the insulin receptor of liver is found to
have mild fasting hyperglycemia (blood
glucose : 132mg/dL versus 101 mg/dL
in controls) and a more striking
hyperglycemia in the fed state (glucose
: 363 mg/dL versus 135 mg/dL in
controls). The mice have higher than
normal levels of glucose-6-
phosphatase in the liver and elevated
levels of insulin in the blood. Explain
these observations (2M)
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Explanation:
Fasting blood sugar test
A fasting blood sugar level from 100 to 125 mg/dL (5.6 to 7.0 mmol/L ) is considered prediabetes. This result is sometimes called impaired fasting glucose. A fasting blood sugar level of 126 mg/dL (7.0 mmol/L ) or higher indicates type 2 diabetes.
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