(3x – 4y) (4x²y + 3xy²); x = 2, y=-1
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= [{(3×2)-{4×(-1)}] × [{4×(2×2)×(-1)} + {3×2(-1×2)}]
= [{(3×2)-{-4}] × [{4×4×-1} + {6×(-2)}]
= [6+4] × [{16×-1}+(-12)]
= 10×[{-16+(-12)}]
= 10×[-38]
= -380
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