4. If the recessive allele is selected against:
a) Which way would the population shift on the graph (ie, to the left or to the right)
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Here's how natural selection can keep a harmful allele in a gene pool: The allele (S) for sickle-cell anemia is a harmful autosomal recessive. It is caused by a mutation in the normal allele (A) for hemoglobin (a protein on red blood cells). ... This keeps the S allele in the gene pool.
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