Question

42. Sulphamethazine is prepared by the condensation of

(A) N-acetyl sulphanilyl chloride with 2-amino 4,6-dimethyl pyridine

(B) N-acetyl sulphanilyl chloride with 2-amino 4,6-dimethyl pyrimidine

(C) N-acetyl sulphanilyl chloride with 2-amino pyridine

(D) N-acetyl sulphanilyl chloride with 2-amino pyrimidine​

Answer 1

i think b option is ur answer

Answer 2

Given:

Sulphamethazine is prepared

To Find:

Sulphamethazine is prepared by the condensation of

(A) N-acetyl sulphanilyl chloride with 2-amino 4,6-dimethyl pyridine

(B) N-acetyl sulphanilyl chloride with 2-amino 4,6-dimethyl pyrimidine

(C) N-acetyl sulphanilyl chloride with 2-amino pyridine

(D) N-acetyl sulphanilyl chloride with 2-amino pyrimidine​

Solution:

4-methyl-2-aminopyrimidine is reacted with 4-acetylaminobenzenesulphonyl chloride to make an acetanilide derivative. Then it is hydrolysed to form  sulphamerazine.