5. A frameshift mutation undergoes reversion to wildtype. What are the ways in which
reversion could occur?
a. deletion of two bases
b. a missense mutation next to the original mutation
c. an inversion within the mutated gene
d. insertion of two bases
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A frameshift mutation is a type of mutation involving the insertion or deletion of a nucleotide in which the number of deleted base pairs is not divisible by three. "Divisible by three" is important because the cell reads a gene in groups of three bases. Each group of three bases corresponds to one of 20 different amino acids used to build a protein. If a mutation disrupts this reading frame, then the entire DNA sequence following the mutation will be read incorrectly.
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