Question

5. All manuals including human being excrete uric acid.​

Answer 1

Answer:

In normal humans, uric acid is excreted in urine. However, uric acid excretion may be impaired by kidney disease, leading to hyperuricemia

Answer 2

Answer:

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Reference Range

The final breakdown product of purine catabolism in humans is uric acid. The liver and intestinal mucosa produce most of the uric acid. The kidneys eliminate two thirds of the uric acid, with the GI tract excreting the other one third. Uric has a pKa of 5.75 and 10.3 and thus is a weak acid. The ionized forms of uric acid, urates, are present in synovial fluid and in plasma; approximately 98% exists as monosodium urate, with a pH of 7.4. [1]

During male puberty, serum urate levels begin to rise from those of childhood. Female levels remain low until until after menopause, when values increase and approximate those of men. Serum urate levels can vary with height, blood pressure, body weight, renal function, and alcohol intake. [2]

Explanation:

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