5. Match the Column I with Column II:
Column 1. Column II i. Autosomal trisomy. p. Turner's Syndrome. ii. Allosomal trisomy q. Mendelian disorder iii. Allosomal Monosomy r. Klinefelter's Syndrome iv. Cystic fibrosis. s. Down's Syndrome
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monosomy and trisomy come under the broad category of aneuploidy. ... Chromosomal basis: Down syndrome is a genetic condition.
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Columns are matched as follows -
i. Autosomal trisomy. s. Down's Syndrome
ii. Allosomal trisomy r. Klinefelter's Syndrome
iii. Allosomal Monosomy p. Turner's Syndrome.
iv. Cystic fibrosis q. Mendelian disorder
- Monosomy is the condition when only copy of chromosome is present. Allosomal refers to sex chromosomes.
- Trisomy refers to presence of three copies of chromosomes. Autosomes are the somatic cells.
- Mendelian disorder is the disorder when single gene is effected leading to a type of disorder.
- In Down's syndrome, there are three copies of chromosome number 21. Klinefelter syndrome is characterized by presence of XXY in males. Turner's syndrome occurs in females where only X chromosome is present. Cystic fibrosis is associated with gene named cystic fibrosis transmembrane conductance regulator (CFTR).
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