Question

5. punctuate: you are left-handed aren't you
A) You are left-handed, aren't you?
B) You, are left-handed, aren't you!
C) You are, left-handed, aren't you...
D) You are left-handed aren't you.
E) You are left-handed aren't you?

Answer 1

A) is the correct answer

Answer 2

The question is clearly indicating a question tag.

Rule: According to the rule the sentence and it's negative tag should be separated with a comma (,) and as the tag is a question, it should be ended with a question mark (?)

So, The corrected sentence be -

                        You are left-handed, aren't you?    {option A}