Question

53. Which one of the following would not give an appreciable
yield of Claisen condensation product?
(a) Ethyl hexanoate
(b) Ethyl-3-methyl hexanoate
(C) Ethyl-2-methyl hexanoate (d) Ethyl-4-methyl hexanoate​

Answer 1

Answer:

The Claisen condensation is a carbon-carbon bond-forming reaction that occurs between two esters, or one ester and another carbonyl compound in the presence of a strong base, resulting in a -keto ester or a -diketone.

But in case of, ethyl 2-methyl hexanoate resulting product will not deprotonate to enolate which is essential for driving the reaction, so it will not perform this reaction.