Question

8) A drug has a serum half-life of 30 minutes in its native form. PEG is conjugated to the drug to improve its pharmacokinetics and the
modified drug is injected intravenously with an initial plasma concentration of 1 mg/ml. After 12 hours, the concentration of drug in serum is
0.5 mg/ml. Calculate the difference between the initial and post-PEGylation half-life of the drug, assuming first order kinetics of elimination
Report answers in hours.​

Answer 1

ऑर ट्रकचे मूळ स्वरूपात 30 मिनिटांचे अर्धशतक आयुष्य असते आणि त्याची गुणवत्ता सुधारण्यासाठी औषधाशी सहजतेने संयोग साधला जातो आणि मुलाखत न देता कनेक्शन गमावल्यामुळे सुधारित समुद्रामध्ये इंजेक्शन दिला जातो.