A 25-year-old man and his wife undergo an infertility workup. His wife's reproductive function is normal. On physical examination he has descended testes that appear decreased in size. A sperm count shows aspermia. A testicular biopsy is performed and on microscopic examination only Sertoli cells are present in the seminiferous tubules. Which of the following laboratory test findings is he most likely to have?
A Increased FSH
B Increased HCG
C Increased alpha-fetoprotein
D Decreased testosterone
E Decreased muellerian inhibiting substance
F Decreased luteinizing hormone
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Answer:
Increased alpha-fetoprotein
Explanation:
An Increase in alpha fetoprotien tells the presence of testicular neoplasm with a yolk sac element.
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