A 3-year-old patient with DiGeorge congenital thymic aplasia presents with a seizure. An elevated serum phosphorus and low serum calcium confirm a hypoparathyroid state. Plasma levels of calcium can be increased most rapidly by the direct action of PTH on which of the following ?
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D.PTH increases plasma calcium levels primarily by mobilizing bone calcium.The main function of the parathyroid gland is to maintain a constant ionized calciumlevel in the extracellular fluid. To do this, PTH stimulates increased plasma calciumlevels, chiefly by mobilizing calcium from bones. Although PTH can also increase renaltubular reabsorption of calcium and intestinal absorption of calcium, these effects dependon adequate dietary ingestion of calcium and thus occur more slowly.
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