A correct order of reactivity of acid derivatives towards nucleophilic attack is
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Reactivity trends
Reactivity trendsThere are five main types of acyl derivatives. Acid halides are the most reactive towards nucleophiles, followed by anhydrides, esters, and amides. ... The reactivity of acyl compounds towards nucleophiles decreases as the basicity of the leaving group increases, as the table shows.
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☑ Reactivity trends
There are five main types of acyl derivatives. Acid halides are the most reactive towards nucleophiles, followed by anhydrides, esters, and amides. ... The reactivity of acyl compounds towards nucleophiles decreases as the basicity of the leaving group increases, as the table shows.
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