Question

A cyclometalated ir(iii) complex as lysosome targeted photodynamic therapeutic agent for integrated imaging and therapy in cancer cells

Answer 1

First of this is a ongoing research and has been proven to cure cancer cells by therapy and integrated imaging. This cyclometalated ir(iii) complex or iridium complexes have shown us a light for cause that the will serve the potency of a drug therapy as a anticancer agent. Cyclometalated iridium (iii) are having great photophysical and photochemical properties which can synthesise and characterise themselves to absorb into carcinoma cells, especially human lung adenocarcinoma or the A549 cancer cells in a short span of time specifically targeting the mitochondrion of the cell. The mechanism you causing ATP or chemical energy depletion and shrinking the mitochondrial cell to a great level in carcinoma cells. The use Organelle-targeted photosensitisers or the PSs are having multi-luminescence imaging and an extensive photodynamic therapy, this causes the cancer cells or the carcinoma to get killed and act as a anti-cancerous cell by a lysosomic-targeted theranostic probe which is applicable for various disease curing.