Question

a major site for synthesis of lipids is

Answer 1

Lipids include fats, waxes, phospholipids, sterols, such as cholesterol, and fat-soluble vitamins. Broadly speaking, there are three possible sites where lipids are synthesized: the smooth endoplasmic reticulum (SER), the cytosol and, in plants specifically, the chloroplast.
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Answer 2

the major site for synthesis of lipids is SER