Question

A model cell contains the intracellular ions Na+, K+, Cl- , and An- (impermeant anions) and the extracellular ions Na+, K+, and Cl- . The concentration (activities) of [Na+]o=125 mmol l-1, [K+]o = 5 mmol l-1, whereas [An- ]i = 123 mmol l-1, [K+]i= 112 mmol l-1. Assume the membrane is permeable to Na+, K+, and Cl- . [ The subscripts i and o refer to inside and outside, respectively]. The relative permeabilities for the ions are pNa/pK=0.02, pCl/pK=0.1

What are the values of [Cl- ]o, [Na+]i, and [Cl- ]i, for this cell to be in equilibrium? (take into account both electrical and osmotic considerations).

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