A person suffering from a disease caused by plasmodium has recurring chills and fever at the time of
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the parasite after its rapid multiplication inside RBCs ruptures them, releasing the stage to enter fresh RBCs
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⭐. They enter the sinusoids of the liver by rupting the cell membrane of the schizont and the liver cells.
⭐. The cryptozoites may enter into fresh liver cells or RBC to continue erythrocytic cycle.
⭐. Finally erythrocytes brust and release merozoites and haemozoin into the blood.
⭐. The release of haemozoin in blood cause chill , fever.
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