Question

A person with a phenotype of HbSS has sickle cell disease. A person with a phenotype of HbAS allele carries the sickle cell trait. A person with a phenotype of HbAA does not have sickle cell disease and does not carry the trait. The Punnett square shows the phenotype of two people carrying the sickle cell trait.

Answer 1

A person with a phenotype of HbSS has sickle cell disease. A person with a phenotype of HbAS allele carries the sickle cell trait. A person with a phenotype of HbAA does not have sickle cell disease and does not carry the trait. The Punnett square in the image shows the resulting progeny after a cross between the two individuals of the genotype, HbAS, who are carrying the sickle cell gene. The probability of offspring getting sickle cell disease turns out to be, 25%.