A person with defective mitochondria get fatigued very fast. Why?
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A champion swimmer, 16-year-old Joe Wise seems a healthy and happy high school junior. He enjoys time with friends, and he’s looking forward to college. But take a closer look, deep into his cells, and something’s not quite right. There’s a malfunction in the tiny capsule-shaped structures—called mitochondria—that power his cells. These abnormal mitochondria cause extreme fatigue and weakness in his legs, trouble breathing and a host of other problems.
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When the mitochondria are defective, the cells do not have enough energy. The unused oxygen and fuel molecules build up in the cells and cause damage. The symptoms of mitochondrial disease can vary.
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