Question

A purine nucleotide is____
(1) AMP
(2)UMP
(3)CMP
(4)TMP​

Answer 1

$\: \: \: \: \: \: (1)amp$

Answer 2

The correct option is (1) AMP

Explanation:

• Adenosine monophosphate (AMP) is changed to inosine monophosphate (IMP) by AMP deaminase, and IMP is subsequently converted back to AMP by adenylosuccinate as an intermediary in the purine nucleotide cycle.

• Three enzyme-catalyzed reactions make up the cycle.

1. The enzyme AMP deaminase catalyses the deamination of the purine nucleotide adenosine monophosphate (AMP) to generate inosine monophosphate (IMP).
2. The enzyme adenylosuccinate synthetase catalyses the production of adenylosuccinate from IMP and the amino acid aspartate, which is connected to the energetically favourable hydrolysis of GTP.
3. Finally, the enzyme adenylosuccinate lyase cleaves adenylosuccinate to liberate fumarate and renew the AMP starting material.