Question

a short essay on biomedical polymers​

Answer 1

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Biological polymers are large molecules composed of many similar smaller molecules linked together in a chain-like fashion. The individual smaller molecules are called monomers. When small organic molecules are joined together, they can form giant molecules or polymers.

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Answer 2

Biomedical polymers have and still continue to play an important role in how we support and treat patients with various diseases through their use in tissue and blood interacting medical devices and drug delivery systems. Today, a wide variety of blood-contacting devices provide the means for the diagnosis, treatment, and support of life until organ transplantation. Their usage warrants their interaction with cells, bacteria, blood, tissue, and sometimes a combination of these complex living systems and the fates of such interactions are critical for applications including biomimetic surfaces, regenerative medicine, immunomodulation, smart biomaterials for drug delivery, and many more. For blood-contacting devices, their surface interactions with blood mostly lead to blood coagulation, inflammation, device failure, and patient complications. Their lifetimes are thus limited to hours and days due to clot formation. Use on the order of months is however needed for many of these devices including vascular grafts, catheters, artificial lungs, extracorporeal circulation circuits, and dialysis membranes, which rely on the free flow of blood over their surfaces. Clots, however halts this flow and causes the devices to fail. This chapter describes prominent challenges and new directions of hemocompatibility and specifically anticlotting biomaterials research.