A specialized form of cell death without an inflammatory response
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Apoptosis does not trigger inflammation, whereas another form of cell death called necrosis—in which the cell membrane is ruptured—is often associated with inflammation (Kerr et al., 1972).
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Necrotic cell death occurs in response to many kinds of insults (e.g. trauma, infarction, toxins, etc.) and therefore is typically the result of a pathological process. ... Apoptotic cells may not stimulate inflammation if they are ingested by phagocytes before they release their intracellular contents.
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