a) Which disease is shown by the family pedigree of Queen Victoria?
b) State the reason for the occurrence of the disease.
c) When does a female become sufferer of the disease?
d) Name the disease caused by trisomy of chromosome no. 21. e) Mention any two symptoms of Down's syndrome.
Answers
Hiii MATe ☺☺
a, hemophilia
AThe pedigree chart of Queen Victoria of England illustrates inheritance of hemophilia A. Queen Victoria herself was a carrier due to a chance mutation. Her children married other royalty and passed the trait throughout the royal families of Europe.
b,
Bacteria. These one-cell organisms are responsible for illnesses such as strep throat, urinary tract infections and tuberculosis
c,
Hemophilia is a rare blood disease that usually occurs in males. In fact, it's extremely rare for women to be born with the condition because of the way it's passed down genetically. A female would need to inherit two copies of the faulty gene — one from each parent — to develop hemophilia A, B or C
d,
A trisomy is a chromosomal condition characterised by an additional chromosome. A person with a trisomy has 47 chromosomes instead of 46. Down syndrome, Edward syndrome and Patau syndrome are the most common forms of trisomy
e,
Decreased or poor muscle tone.
Short neck, with excess skin at the back of the neck.
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Answer:
a. Hemophilia A
b. It’s caused by a defect in the gene that determines how the body makes factors VIII, IX, or XI. These genes are located on the X chromosome, making hemophilia an X-linked recessive disease.
Each person inherits two sex chromosomes from their parents. Females have two X chromosome
hope it helps