(a) Why does DNA replication occur in small replication forks and not in its entire length?
(b) Why is DNA replication continuous and discontinuous in a replication fork?
(c) State the importance of origin of replication in a replication fork.
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A. DNA replication requires separate strands of DNA. They get this in the form of the replication fork. The separation of DNA requires energy, and hence the complete separation of DNA is not possible at once.
B. Continuous and discontinuous replication occurs due to directional specificity of DNA polymerase. It works only in 5'-3' direction hence works continuously in a straight line. For opposite DNA strand, 3'-5' DNA polymerase has to work in breaks and hence discontinuous replication occurs.
C. Origin of replication is the site where DNA replication starts, thus it is important to direct proteins and enzymes and start binding for DNA replication.
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