ABO incompatibility differ from Rh factor incompatibility in
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A major cause of HDN is an incompatibility of the Rh blood group between the mother and fetus. Most commonly, hemolytic disease is triggered by the D antigen, although other Rh antigens, such as c, C, E, and e, can also cause problems. ... HDN due to ABO incompatibility is usually less severe than Rh incompatibility
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