Question

According to Chargaff's rule, base pairing in DNA should resemble which of the following?
A = T; C = G
A = C; T = G
A = G; T = U
A = U; C = G

Answer 1

According to Chargaff's rule, base pairing in DNA should resemble with A = T; C = G

Chargaff's Rule:

According to this rule,

• Adenine = Thymine

• Guanine = Cytosine

(Purines = Pyrimidines)

But their sum's are not equal to each other.

i.e. A + T ≠ G + C

A nucleotide is the monomers whose repetition makes polynucleotides or nucleic acid like DNA and RNA.

Nucleotide consists of three components:

1) Nitrogenous base

It further consists of two types i.e. Purine and Pyrimidine.

→ Purine = Adenine, Guanine

→ Pyrimidine = Cytosine, Thymine

2) Pentose sugar

3) Phosphoric acid

A nucleoside is formed by the combination of nitrogeneous base and pentose sugar.

In the structure of DNA (double-stranded structure), Purine always makes a hydrogen bond with Pyrimidine.

Adenine (A) makes the double bond with Thymine (T) and Cytosine (C) make a triple hydrogen bond with Guanine (G).

Answer 2

$</p><p>\huge{\tt{\pink {Hello!!! }}}$

$</p><p>\green{\tt{Chargraff's \: Rule \: - }}$

According to Chargraff's ruler of base pairings in DNA ,

$</p><p>\tt{\purple{Adenine \: => \: Thyamine }}$

$</p><p>\tt{\purple{Cytocynine\: =>\: Guanine}}$

But Their Sum Is Unequal ...

$</p><p>\tt{\orange{Hence \: Option_{2} \: Is \: Correct . }}$