Chemistry, asked by jyotiarora1990, 1 year ago

Acid derivatives reactivity order for nucleophilic substitution

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Answered by arjun7774
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✔️Reactivity trends. There are five main types of acyl derivatives. Acid halides are the most reactive towards nucleophiles, followed by anhydrides, esters, and amides. Carboxylate ions are essentially unreactive towards nucleophilic substitution, since they possess no leaving group.✴️

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