Acromegaly and Gigantism are similar or not?If not,what are the differences?
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Answer:
Gigantism refers to abnormally high linear growth (see the image below) due to excessive action of insulinlike growth factor I (IGF-I) while the epiphyseal growth plates are open during childhood. Acromegaly is the same disorder of IGF-I excess but occurs after the growth plate cartilage fuses in adulthood.
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They are similar
Acromegaly is a condition in which a benign tumor in the pituitary gland produces too much growth hormone in an adult who no longer needs growth hormone to grow. Gigantism is a similar condition, but is specific to children who are still able to grow abnormally in response to the abnormally high amount of growth hormone produced by the pituitary tumor.
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