Question

Action mechanism of alkalyting agents is​

Answer 1

Answer:

Alkylating agents act by cross-linking strands of DNA, particularly at the N-7 position of guanine. They are nonspecific for cell cycle phase and are thus active during most parts of the cell cycle.

1- Classical alkylators: Aziridine, chlorambucil, cyclophosphamide, estramustine, ifosfa...

2- Nonclassical alkylators: Altretamine, dacarbazine, procarbazine

3- Platinum complexes: Carboplatin, cisplatin, oxaliplatin