Action mechanism of alkalyting agents is
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Alkylating agents act by cross-linking strands of DNA, particularly at the N-7 position of guanine. They are nonspecific for cell cycle phase and are thus active during most parts of the cell cycle.
1- Classical alkylators: Aziridine, chlorambucil, cyclophosphamide, estramustine, ifosfa...
2- Nonclassical alkylators: Altretamine, dacarbazine, procarbazine
3- Platinum complexes: Carboplatin, cisplatin, oxaliplatin
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