Question

Advantages of nsaids without carboxylic acid over nsaids with carboxylic acid

Answer 1

The carboxylic acid group (-COOH) present in classical NSAIDs is partly responsible for the gastric toxicity associated with the administration of these drugs. This concept has been extensively proven using NSAID prodrugs.

Answer 2

Explanation:

$<p style ="Color:red; font-family: cursive; background:black;font size25px;"> A carboxylic acid is an organic compound that contains a carboxyl group (C(=O)OH) attached to an R-group. The general formula of a carboxylic acid is R–COOH, with R referring to the alkyl group. Carboxylic acids occur widely. Important examples include the amino acids and fatty acids.$