Advantages of selectable marker
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This element is required for the maintenance of the plasmid in the cell. Under the selective conditions, only cells that contain plasmids with the appropriate selectable marker can survive. Commonly, genes that confer resistance to various antibiotics are used as selective markers in cloning vectors.
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A selectable marker will protect the organism from a selective agent that would normally kill it or prevent its growth. In most applications, only one in a several million or billion cells will take up DNA.
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