Question

After a batch fermentation, the system is dismantled and approximately 75% of cell mass is suspended in the liquid phase of 2l, while 25% is attached to the reactor walls and internals in a thick film (0.3cm). Work with radioactive tracers shows that 50% of the target product (intracellular) is associated with each cell fraction. The productivity of this reactor is 2 g/l at 2l scale. What would be the productivity at l scale if both reactor had a height-to-diameter ratio of 2 to1?

Answer 1

cell mass is suspended in the liquid phase (2 l ), while 25% is attached to the reactor walls and internals in a thick film (ca. 0.3 cm). Work with radioactive tracers shows that 50 cm.

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