Question

Alkylation of enamine obeys which mechanism?

a) SN2 b) SN1

c) AAc2 d) BAc2

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Answer 1

Answer:

The Stork enamine alkylation, involves the addition of an enamine to an alpha, beta-unsaturated carbonyl acceptor in a process similar to the Michael reaction.[1] The product is then hydrolyzed by an aqueous acid to produce a 1,5-dicarbonyl compound.

The process:

formation of an enamine from a ketone

addition of the enamine to an alpha, beta-unsaturated aldehyde or ketone

hydrolysis of the enamine back to a ketone