ALS (Amyotrophic Lateral Sclerosis or Lou Gehrig's disease) can start off with something as
simple as a weak feeling in your hands or feet. It's a disease that attacks the brain cells that control a lot
of your muscle movement. Signs of ALS can appear gradually. ALS is a progressive nervous system
(neurological) disease that destroys nerve cells and causes disability. ALS is often called Lou Gehrig's
disease, after the famous baseball player who was diagnosed with it. As the disease progresses, muscle
weakness spreads to other parts of the body, making everyday tasks such as buttoning a shirt or turning a
key challenging.
You may notice a funny feeling in your hand that makes it harder to grip the steering wheel.
Some common early symptoms include: Stumbling, a hard time holding items with your hands, slurred
speech, swallowing problems, muscle cramps and muscle stiffness.
ALS is inherited in 5 to 10 % of cases. Smoking is the only likely environmental risk factor for
ALS. Some evidence suggests that exposure to lead or other substances in the workplace or at home may
be linked to ALS. Much study has been done, but no single agent or chemical has been consistently
associated with ALS. Recent studies indicate that people who have served in the military are at higher
risk of ALS, may be due to exposure to certain metals or chemicals,traumatic injuries, viral infections,
and intense exertion.
ALS doesn't usually affect your bowel or bladder control, your senses or your thinking ability. It's
possible to remain actively involved with your family and friends.
There is currently no cure, and treatment aims to relieve symptoms, provide social and emotional support,
and possibly slow disease progression.
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Answers
Answer:
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Explanation:
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ALS often begins with muscle twitching and weakness in a limb, or slurred speech. Eventually, ALS affects control of the muscles needed to move, speak, eat and breathe. There is no cure for this fatal disease.
More Information:
ALS affects the nerve cells that control voluntary muscle movements such as walking and talking (motor neurons). ALS causes the motor neurons to gradually deteriorate, and then die. Motor neurons extend from the brain to the spinal cord to muscles throughout the body. When motor neurons are damaged, they stop sending messages to the muscles, so the muscles can't function.
- ALS is inherited in 5% to 10% of people. For the rest, the cause isn't known.
- Researchers continue to study possible causes of ALS. Most theories center on a complex interaction between genetic and environmental factors.
Risk factorsEstablished risk factors for ALS include:
- Heredity. Five to 10 percent of the people with ALS inherited it (familial ALS). In most people with familial ALS, their children have a 50-50 chance of developing the disease.
- Age. ALS risk increases with age, and is most common between the ages of 40 and the mid-60s.
- Sex. Before the age of 65, slightly more men than women develop ALS. This sex difference disappears after age 70.
- Genetics. Some studies examining the entire human genome found many similarities in the genetic variations of people with familial ALS and some people with noninherited ALS. These genetic variations might make people more susceptible to ALS.
- Environmental factors, such as the following, might trigger ALS.
- Smoking. Smoking is the only likely environmental risk factor for ALS. The risk seems to be greatest for women, particularly after menopause.
- Environmental toxin exposure. Some evidence suggests that exposure to lead or other substances in the workplace or at home might be linked to ALS. Much study has been done, but no single agent or chemical has been consistently associated with ALS.
- Military service. Studies indicate that people who have served in the military are at higher risk of ALS. It's unclear what about military service might trigger the development of ALS. It might include exposure to certain metals or chemicals, traumatic injuries, viral infections, and intense exertion.
As the disease progresses, ALS causes complications, such as:
- Breathing problems Over time, ALS paralyzes the muscles you use to breathe. You might need a device to help you breathe at night, similar to what someone with sleep apnea might wear. For example, you may be given continuous positive airway pressure (CPAP) or bilevel positive airway pressure (BiPAP) to assist with your breathing at night.
- Some people with advanced ALS choose to have a tracheostomy — a surgically created hole at the front of the neck leading to the windpipe (trachea) — for full-time use of a respirator that inflates and deflates their lungs.
- The most common cause of death for people with ALS is respiratory failure. On average, death occurs within three to five years after symptoms begin. However, some people with ALS live 10 or more years.
- Most people with ALS develop trouble speaking. This usually starts as occasional, mild slurring of words, but becomes more severe. Speech eventually becomes difficult for others to understand, and people with ALS often rely on other communication technologies to communicate.
- People with ALS can develop malnutrition and dehydration from damage to the muscles that control swallowing. They are also at higher risk of getting food, liquids or saliva into the lungs, which can cause pneumonia. A feeding tube can reduce these risks and ensure proper hydration and nutrition.
Some people with ALS have problems with memory and decision-making, and some are eventually diagnosed with a form of dementia called frontotemporal dementia.