amorphous silicon is used in
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it is a metalloid . silicon is metalloid . ok
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Amorphous silica (SiO2) is an inorganic material commonly used in semiconductor circuits to isolate different conducting regions. Due to its mechanical resistance, high dielectric strength, and selectivity for chemical modification, amorphous silica has also become a key material in microelectronics and chromatography. Because of its unique properties, silica is quintessential for a broad range of applications: chips, optical fibers, and telescope glasses are manufacture on silica. Furthermore, molecular biologists employ silica in resins and optical beads to study the biomacromolecules.
In recent years, the synergy between molecular biology and nanotechnology has opened up opportunities for many applications that involve macromolecules and silica, such as nanoelectronics, self-assembly of nanostructures, microfluidics, DNA microarray technology and nanopore sensors. The picture on the left side shows one of such nanodevices, a MOS nanopore manufactured on a poly-Silicon-Silica-Silicon membrane and a single-stranded DNA molecule (blue) translocating through it. It has been proposed that nanopores could be used to sequence DNA with single base resolution, leading to a fast and cheap DNA sequencing technology, which promises to have a enormous impact in life sciences and personal medicine. Therefore, an atomic level understanding of the interactions between biomolecules and silica is now central for further development of bionanotechnology applications.
Currently, no experimental technique is yet sensitive enough to resolve atomic-scale dynamics at the amorphous interface. Molecular dynamics simulations can be tailored to study those systems, becoming unique imaging tools. However, modeling systems that combine amorphous silica and biomolecules imposes a variety of challenges to modelers.
Until recently, computer simulations of biomacromolecules and inorganic materials, such as amorphous silica and DNA, have evolved independently from each other, and joining the expertise from both areas is a formidable task. Our previous pioneering work in nanobiotechnology was focused on crystalline inorganic structures, such asgold and silicon nitride. In this website, we briefly describe the work that the TCBG has performed to study nanosensors based of amorphous silica.
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In recent years, the synergy between molecular biology and nanotechnology has opened up opportunities for many applications that involve macromolecules and silica, such as nanoelectronics, self-assembly of nanostructures, microfluidics, DNA microarray technology and nanopore sensors. The picture on the left side shows one of such nanodevices, a MOS nanopore manufactured on a poly-Silicon-Silica-Silicon membrane and a single-stranded DNA molecule (blue) translocating through it. It has been proposed that nanopores could be used to sequence DNA with single base resolution, leading to a fast and cheap DNA sequencing technology, which promises to have a enormous impact in life sciences and personal medicine. Therefore, an atomic level understanding of the interactions between biomolecules and silica is now central for further development of bionanotechnology applications.
Currently, no experimental technique is yet sensitive enough to resolve atomic-scale dynamics at the amorphous interface. Molecular dynamics simulations can be tailored to study those systems, becoming unique imaging tools. However, modeling systems that combine amorphous silica and biomolecules imposes a variety of challenges to modelers.
Until recently, computer simulations of biomacromolecules and inorganic materials, such as amorphous silica and DNA, have evolved independently from each other, and joining the expertise from both areas is a formidable task. Our previous pioneering work in nanobiotechnology was focused on crystalline inorganic structures, such asgold and silicon nitride. In this website, we briefly describe the work that the TCBG has performed to study nanosensors based of amorphous silica.
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AbhinavAtreus:
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