An immigrant from eastern Europe is rushed into the emergency room with nausea, vomiting, diarrhea, and abdominal pain. His family indicates he has eaten wild mushrooms. They have brought a bag of fresh, uncooked mushrooms from a batch he had not yet prepared. You note the presence of Amanita phalloides, the death-cap mushroom. A liver biopsy indicates massive hepatic necrosis. Care is supportive. A major toxin of the death-cap mushroom is the hepatotoxic octapeptide α-amanitin, which inhibits
DNA primase
RNA nuclease
DNA ligase
RNA polymerase
RNA/DNA endonuclease
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An immigrant from eastern Europe is rushed into the emergency room with nausea, vomiting, diarrhea, and abdominal pain. His family indicates he has eaten wild mushrooms. They have brought a bag of fresh, uncooked mushrooms from a batch he had not yet prepared. You note the presence of Amanita phalloides, the death-cap mushroom. A liver biopsy indicates massive hepatic necrosis. Care is supportive. A major toxin of the death-cap mushroom is the hepatotoxic octapeptide -amanitin, which inhibits which of the following?
a.DNA primase
b.RNA nuclease
c.DNA ligase
d.RNA polymerase
e.RNA/DNA endonuclease
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* Biochem and genetics....
#264814
kaham - 01/26/08 14:45
An immigrant from eastern Europe is rushed into the emergency room with nausea, vomiting, diarrhea, and abdominal pain. His family indicates he has eaten wild mushrooms. They have brought a bag of fresh, uncooked mushrooms from a batch he had not yet prepared. You note the presence of Amanita phalloides, the death-cap mushroom. A liver biopsy indicates massive hepatic necrosis. Care is supportive. A major toxin of the death-cap mushroom is the hepatotoxic octapeptide -amanitin, which inhibits which of the following?
a.DNA primase
b.RNA nuclease
c.DNA ligase
d.RNA polymerase
e.RNA/DNA endonuclease
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* Re:Biochem and genetics....
#1143855
kaham - 01/26/08 14:49
An immigrant family from rural Mexico brings their 3-month-old child to the emergency room because of whistling inspiration (stridor) and high fever. The child's physician is perplexed because the throat examination shows a gray membrane almost occluding the larynx. A senior physician recognizes diphtheria, now rare in immunized populations. The child is intubated, antitoxin is administered, and antibiotic therapy is initiated. Diphtheria toxin is often lethal in unimmunized persons because it ..
a. Inhibits initiation of protein synthesis by preventing the binding of GTP to the 40S ribosomal subunit
b. Binds to the signal recognition particle receptor on the cytoplasmic face of the endoplasmic reticulum receptor
c. Blocks elongation of proteins by inactivating elongation factor 2 (EF-2, or translocase)
d. Causes deletions of amino acid by speeding up the movement of peptidyl-tRNA from the A site to the P site
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* Biochem and genetics....
#264814
kaham - 01/26/08 14:45
An immigrant from eastern Europe is rushed into the emergency room with nausea, vomiting, diarrhea, and abdominal pain. His family indicates he has eaten wild mushrooms. They have brought a bag of fresh, uncooked mushrooms from a batch he had not yet prepared. You note the presence of Amanita phalloides, the death-cap mushroom. A liver biopsy indicates massive hepatic necrosis. Care is supportive. A major toxin of the death-cap mushroom is the hepatotoxic octapeptide -amanitin, which inhibits which of the following?
a.DNA primase
b.RNA nuclease
c.DNA ligase
d.RNA polymerase
e.RNA/DNA endonuclease
Report Abuse
* Re:Biochem and genetics....
#1143855
kaham - 01/26/08 14:49
An immigrant family from rural Mexico brings their 3-month-old child to the emergency room because of whistling inspiration (stridor) and high fever. The child's physician is perplexed because the throat examination shows a gray membrane almost occluding the larynx. A senior physician recognizes diphtheria, now rare in immunized populations. The child is intubated, antitoxin is administered, and antibiotic therapy is initiated. Diphtheria toxin is often lethal in unimmunized persons because it ..
a. Inhibits initiation of protein synthesis by preventing the binding of GTP to the 40S ribosomal subunit
b. Binds to the signal recognition particle receptor on the cytoplasmic face of the endoplasmic reticulum receptor
c. Blocks elongation of proteins by inactivating elongation factor 2 (EF-2, or translocase)
d. Causes deletions of amino acid by speeding up the movement of peptidyl-tRNA from the A site to the P site
Report Abuse
* Re:Biochem and genetics....
#1143868
kaham - 01/26/08 14:54
teenage girl is brought to the medical center because of her complaints that she gets too tired when asked to participate in gym class. A consulting neurologist finds muscle weakness in the girl's arms and legs. When no obvious diagnosis can be made, biopsies of her muscles are taken for tests. Chemistries reveal greatly elevated amounts of triacylglycerides esterified with primarily long-chain fatty acids. Pathology reports the presence of significant numbers of lipid vacuoles