Biology, asked by pala5927, 1 year ago

An inhibitor of nonhomologous end-joining abrogates double-strand break repair and impedes cancer progression

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Answered by Dhivishvarshan

DNA Ligase IV is responsible for sealing of double-strand breaks (DSBs) during nonhomologous end-joining (NHEJ). Inhibiting Ligase IV could result in amassing of DSBs, thereby serving as a strategy toward treatment of cancer.

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