Anaemia due to
maturation defect is
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Defective maturation of red cells leads to premature destruction of nucleated red cell precursors before they leave the haematopoietic bone marrow, which results in expansion of the marrow, haemolytic jaundice, peripheral signs of increased erythroid turnover on blood films, and (in long-standing disorders) iron overload due to enhanced absorption...
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abnormal erythroid maturation is the part of underlining mechanism leading to the micro sitting anaemia. anaemia can be due to defect in the production or destruction of the red blood cells.
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