Anaphase promoting complex APC
is a protein degradation machinery
necessary for proper mitosis of animal
cells. If APC is defective in human cell,
which of the following is expected to
occur?
a. Chromosomes will be fragmented
b. Chromosomes will not condense
c. Chromosomes will not segregate
d. Recombination of chromosomes
will occur
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Answer: C
Explanation: Anaphase promoting complex (APC) is a protein degradation machinery necessary for proper mitosis of animal cells.
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Answer...
✔️Option c. chromosomes will not segregate .
→Anaphase Promoting Complex or APC is a protein necessary for separation of daughter chromosomes during anaphase.
→ It regulates chromosome segregation and anaphase progression by targeting key factors for degradation.
→ If APC is defective then the chromosomes will fail to segregate (separate) during anaphase.
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