Question

Anaphase promoting complex (APC) is a protein
degradation machinery necessary for proper
mitosis of animal cells. If APC is defective in a
human cell, which of the following is expected to
occur?
[NEET - 2017]
(1) Chromosomes will not condense
(2)
Chromosomes will be fragmented
(3) Chromosomes will not segregate
(4) Recombination of chromosome arms will occur​

Answer 1

Answer:

If APC is defective in a human cell, which of the following is expected to occur. Solution : Anaphase Promoting Complex (APC) is a protein necessary for separation of daughter chromosomes during anaphase. If APC is defective then the chromosomes will fail to segregate during anaphase.

Answer 2

Answer:

Option C is correct

Explanation:

If anaphase promoting complex is deactive in human cell , the chromosomes will not segregate during anaphase of mitosis . APC triggers the transition from metaphase to anaphase by tagging specific proteins for degradation