Question

aneuploidy of chromosome in human being result in certain disorder draw out the possibility of the karyotype in this common disorder of this kind in human being and its consequences in individuals

Answer 1

Changes in a cell's genetic material are called mutations. In one form of mutation, cells may end up with an extra or missing chromosome.

Each species has a characteristic chromosome number, such as 4646chromosomes for a typical human body cell. In organisms with two full chromosomes sets, such as humans, this number is given the name 2n2n. When an organism or cell contains 2n2nchromosomes (or some other multiple of nn), it is said to be euploid, meaning that it contains chromosomes correctly organized into complete sets (eu- = good).

If a cell is missing one or more chromosomes, it is said to be aneuploid(an- = not, "not good"). For instance, human somatic cells with chromosome numbers of (2n-1) = 45(2n−1)=45 or (2n + 1) = 47(2n+1)=47 are aneuploid. Similarly, a normal human egg or sperm has just one set of chromosomes (n = 23n=23). An egg or sperm with (n-1) = 22(n−1)=22 or (n+1) = 24(n+1)=24 chromosomes is considered to be aneuploid.